Phosphorylation of the androgen receptor at Ser81 is co‐sustained by CDK1 and CDK9 and leads to AR‐mediated transactivation in prostate cancer

Androgen receptor (AR) is the principal molecule in prostate cancer (PCa) etiology and therapy. AR re‐activation still remains a major challenge during treatment of castration‐resistant prostate cancer (CRPC) tumors that relapse after castration therapies. Recent reports have indicated the enrichmen...

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Dettagli Bibliografici
Pubblicato in:Mol Oncol
Autori principali: Gao, XinTao, Liang, Jiaqian, Wang, LiYang, Zhang, Zhaoyang, Yuan, Penghui, Wang, Jiaxin, Gao, Yanfei, Ma, Fen, Calagua, Carla, Ye, Huihui, Voznesensky, Olga, Wang, Shaogang, Wang, Tao, Liu, Jihong, Chen, Shaoyong, Liu, Xiaming
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2021
Soggetti:
Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8253089/
https://ncbi.nlm.nih.gov/pubmed/33932081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12968
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