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Roles of chromophore and apo-protein in neocarzinostatin action.

The methanol-extractable, nonprotein chromophore of the antitumor, protein antibiotic neocarzinostatin (NCS) has at least the full activity of the parent compound in inhibiting DNA synthesis and growth of HeLa cells and in causing DNA strand breaks in vivo and in vitro. In vitro DNA strand scission...

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Autors principals: Kappen, L S, Napier, M A, Goldberg, I H
Format: Artigo
Idioma:Inglês
Publicat: 1980
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC348631/
https://ncbi.nlm.nih.gov/pubmed/6445563
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