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Activation and inactivation of neocarzinostatin-induced cleavage of DNA.
The possible role of free radicals in the mechanism of neocarzinostatin (NCS) action was studied. While mercaptene markedly stimulate the ability of NCS to degrade DNA, they also rapidly inactivate the antibiotic in a preincubation and at higher concentration inhibit the degradation reaction. The ra...
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| Main Authors: | , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1978
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC342218/ https://ncbi.nlm.nih.gov/pubmed/151264 |
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