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Roles of chromophore and apo-protein in neocarzinostatin action.

The methanol-extractable, nonprotein chromophore of the antitumor, protein antibiotic neocarzinostatin (NCS) has at least the full activity of the parent compound in inhibiting DNA synthesis and growth of HeLa cells and in causing DNA strand breaks in vivo and in vitro. In vitro DNA strand scission...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Proc Natl Acad Sci U S A
Prif Awduron: Kappen, L S, Napier, M A, Goldberg, I H
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 1980
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC348631/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6445563/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.77.4.1970
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