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Identification of thymidine-5′-aldehyde at DNA strand breaks induced by neocarzinostatin chromophore

Snake venom phosphodiesterase or endonuclease S1 digestion of neocarzinostatin chromophore-treated DNA, labeled in its thymidine residues, liberates an unusual labeled nucleoside from the 5′ end of a drug-induced break. This substance, isolated by reverse-phase HPLC, possesses carbons from both the...

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Bibliografische gegevens
Hoofdauteurs: Kappen, Lizzy S., Goldberg, Irving H., Liesch, Jerrold M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1982
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC345828/
https://ncbi.nlm.nih.gov/pubmed/16593156
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