Roles of chromophore and apo-protein in neocarzinostatin action.
The methanol-extractable, nonprotein chromophore of the antitumor, protein antibiotic neocarzinostatin (NCS) has at least the full activity of the parent compound in inhibiting DNA synthesis and growth of HeLa cells and in causing DNA strand breaks in vivo and in vitro. In vitro DNA strand scission...
Guardat en:
| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
1980
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC348631/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6445563/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.77.4.1970 |
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