Mice carrying a complete deletion of the talin2 coding sequence are viable and fertile

Mice homozygous for several Tln2 gene targeted alleles are viable and fertile. Here we show that although the expression of talin2 protein is drastically reduced in muscle from these mice, other tissues continue to express talin2 albeit at reduced levels. We therefore generated a Tln2 allele lacking...

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Detaylı Bibliyografya
Asıl Yazarlar: Debrand, Emmanuel, Conti, Francesco J., Bate, Neil, Spence, Lorraine, Mazzeo, Daniela, Pritchard, Catrin A., Monkley, Susan J., Critchley, David R.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Academic Press 2012
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3485561/
https://ncbi.nlm.nih.gov/pubmed/22925892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2012.08.061
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