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Endothelial cell talin1 is essential for embryonic angiogenesis
Using Tln1(fl/fl);CreER mice, we show that tamoxifen-induced inactivation of the talin1 gene throughout the embryo produces an angiogenesis phenotype that is restricted to newly forming blood vessels. The phenotype has a rapid onset in early embryos, resulting in vessel defects by 48 h and death of...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3025397/ https://ncbi.nlm.nih.gov/pubmed/21081121 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2010.11.010 |
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