Talin 2 is a large and complex gene encoding multiple transcripts and protein isoforms

Talins are large adaptor proteins that link the integrin family of adhesion molecules to F-actin. In vertebrates, there are two talin genes. Talin 1 is essential for integrin-mediated cell adhesion; the role of talin 2 is unclear. Here we report a detailed analysis of mammalian talin 2. This reveals...

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Bibliographic Details
Main Authors: Debrand, Emmanuel, El Jai, Yasmine, Spence, Lorraine, Bate, Neil, Praekelt, Uta, Pritchard, Catrin A, Monkley, Susan J, Critchley, David R
Format: Artigo
Language:Inglês
Published: Blackwell Publishing Ltd 2009
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2702505/
https://ncbi.nlm.nih.gov/pubmed/19220457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1742-4658.2009.06893.x
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