New isoform-specific monoclonal antibodies reveal different sub-cellular localisations for talin1 and talin2

Talins are adaptor proteins that connect the integrin family of cell adhesion receptors to cytoskeletal actin. Vertebrates express two closely related talins encoded by separate genes, and while it is well established that talin1 plays a key role in cell adhesion and spreading, little is known about...

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Main Authors: Praekelt, Uta, Kopp, Petra M., Rehm, Kerstin, Linder, Stefan, Bate, Neil, Patel, Bipin, Debrand, Emmanuel, Manso, Ana Maria, Ross, Robert S., Conti, Franceso, Zhang, Ming-Zhi, Harris, Raymond C., Zent, Roy, Critchley, David R., Monkley, Susan J.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3629562/
https://ncbi.nlm.nih.gov/pubmed/22306379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejcb.2011.12.003
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