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Mice carrying a complete deletion of the talin2 coding sequence are viable and fertile

Mice homozygous for several Tln2 gene targeted alleles are viable and fertile. Here we show that although the expression of talin2 protein is drastically reduced in muscle from these mice, other tissues continue to express talin2 albeit at reduced levels. We therefore generated a Tln2 allele lacking...

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Detalhes bibliográficos
Main Authors: Debrand, Emmanuel, Conti, Francesco J., Bate, Neil, Spence, Lorraine, Mazzeo, Daniela, Pritchard, Catrin A., Monkley, Susan J., Critchley, David R.
Formato: Artigo
Idioma:Inglês
Publicado em: Academic Press 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3485561/
https://ncbi.nlm.nih.gov/pubmed/22925892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2012.08.061
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