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Talin 1 and 2 are required for myoblast fusion, sarcomere assembly and the maintenance of myotendinous junctions

Talin 1 and 2 connect integrins to the actin cytoskeleton and regulate the affinity of integrins for ligands. In skeletal muscle, talin 1 regulates the stability of myotendinous junctions (MTJs), but the function of talin 2 in skeletal muscle is not known. Here we show that MTJ integrity is affected...

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Библиографические подробности
Главные авторы: Conti, Francesco J., Monkley, Sue J., Wood, Malcolm R., Critchley, David R., Müller, Ulrich
Формат: Artigo
Язык:Inglês
Опубликовано: Company of Biologists 2009
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2761109/
https://ncbi.nlm.nih.gov/pubmed/19793892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.035857
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