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Progressive myopathy and defects in the maintenance of myotendinous junctions in mice that lack talin 1 in skeletal muscle

The development and function of skeletal muscle depend on molecules that connect the muscle fibre cytoskeleton to the extracellular matrix (ECM). β1 integrins are ECM receptors in skeletal muscle, and mutations that affect the α7β1 integrin cause myopathy in humans. In mice, β1 integrins control myo...

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Hlavní autoři: Conti, Francesco J., Felder, Amanda, Monkley, Sue, Schwander, Martin, Wood, Malcolm R., Lieber, Richard, Critchley, David, Müller, Ulrich
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2562324/
https://ncbi.nlm.nih.gov/pubmed/18434420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.015818
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