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Transcription and translation are primary targets of Pim kinase inhibitor SGI-1776 in mantle cell lymphoma
Proviral integration site for Moloney murine leukemia virus (Pim) kinases are serine/threonine/tyrosine kinases and oncoproteins that promote tumor progression. Three isoforms of Pim kinases have been identified and are known to phosphorylate numerous substrates, with regulatory functions in transcr...
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| Hlavní autoři: | , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society of Hematology
2012
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3482859/ https://ncbi.nlm.nih.gov/pubmed/22955922 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-02-412643 |
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