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Combination of Pim kinase inhibitor, SGI-1776, with bendamustine in B-cell lymphoma
SGI-1776 is a small molecule Pim kinase inhibitor that primarily targets c-Myc-driven transcription and cap-dependent translation in mantle cell lymphoma (MCL) cells. Bendamustine is an alkylating chemotherapeutic agent approved for use in B-cell lymphoma that is known to induce DNA damage and to in...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3951504/ https://ncbi.nlm.nih.gov/pubmed/24290221 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clml.2013.05.024 |
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