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Insulin stimulation of SREBP-1c processing in transgenic rat hepatocytes requires p70 S6-kinase
Insulin activates sterol regulatory element-binding protein-1c (SREBP-1c) in liver, thereby increasing fatty acid and triglyceride synthesis. We created a line of transgenic rats that produce epitope-tagged human SREBP-1c in liver under control of the constitutive apolipoprotein E promoter/enhancer....
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| 主要な著者: | , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3479583/ https://ncbi.nlm.nih.gov/pubmed/22927400 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1213343109 |
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