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TCR signaling via Tec kinase ITK and interferon regulatory factor 4 (IRF4) regulates CD8(+) T-cell differentiation
CD8(+) T-cell development in the thymus generates a predominant population of conventional naive cells, along with minor populations of “innate” T cells that resemble memory cells. Recent studies analyzing a variety of KO or knock-in mice have indicated that impairments in the T-cell receptor (TCR)...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3478592/ https://ncbi.nlm.nih.gov/pubmed/23011795 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1205742109 |
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