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Graded levels of IRF4 regulate CD8(+) T cell differentiation and expansion, but not attrition, in response to acute virus infection()
In response to acute virus infections, CD8(+) T cells differentiate to form a large population of short-lived effectors and a stable pool of long-lived memory cells. The characteristics of the CD8(+) T cell response are influenced by TCR affinity, antigen dose, and the inflammatory cytokine milieu d...
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| Autori principali: | , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4080788/ https://ncbi.nlm.nih.gov/pubmed/24835398 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1303187 |
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