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The Tec kinases Itk and Rlk regulate conventional versus innate T-cell development
Tec family kinases are important components of antigen receptor signaling pathways in B cells, T cells, and mast cells. In T cells, three members of this family, Itk, Rlk, and Tec, are expressed. In the absence of Itk and Rlk, T-cell receptor signaling is impaired, with defects in mitogen-activated...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2669323/ https://ncbi.nlm.nih.gov/pubmed/19290924 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-065X.2008.00746.x |
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