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The Tec kinases Itk and Rlk regulate conventional versus innate T-cell development

Tec family kinases are important components of antigen receptor signaling pathways in B cells, T cells, and mast cells. In T cells, three members of this family, Itk, Rlk, and Tec, are expressed. In the absence of Itk and Rlk, T-cell receptor signaling is impaired, with defects in mitogen-activated...

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Main Authors: Prince, Amanda L., Yin, Catherine C., Enos, Megan E., Felices, Martin, Berg, Leslie J.
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2669323/
https://ncbi.nlm.nih.gov/pubmed/19290924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-065X.2008.00746.x
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