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Entorhinal cortical neurons are the primary targets of FUS mislocalization and ubiquitin aggregation in FUS transgenic rats

Ubiquitin-positive inclusion containing Fused in Sarcoma (FUS) defines a new subtype of frontotemporal lobar degeneration (FTLD). FTLD is characterized by progressive alteration in cognitions and it preferentially affects the superficial layers of frontotemporal cortex. Mutation of FUS is linked to...

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Autors principals: Huang, Cao, Tong, Jianbin, Bi, Fangfang, Wu, Qinxue, Huang, Bo, Zhou, Hongxia, Xia, Xu-Gang
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3471393/
https://ncbi.nlm.nih.gov/pubmed/22833456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/dds299
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