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Entorhinal cortical neurons are the primary targets of FUS mislocalization and ubiquitin aggregation in FUS transgenic rats

Ubiquitin-positive inclusion containing Fused in Sarcoma (FUS) defines a new subtype of frontotemporal lobar degeneration (FTLD). FTLD is characterized by progressive alteration in cognitions and it preferentially affects the superficial layers of frontotemporal cortex. Mutation of FUS is linked to...

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Detalhes bibliográficos
Main Authors: Huang, Cao, Tong, Jianbin, Bi, Fangfang, Wu, Qinxue, Huang, Bo, Zhou, Hongxia, Xia, Xu-Gang
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3471393/
https://ncbi.nlm.nih.gov/pubmed/22833456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/dds299
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