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Entorhinal cortical neurons are the primary targets of FUS mislocalization and ubiquitin aggregation in FUS transgenic rats

Ubiquitin-positive inclusion containing Fused in Sarcoma (FUS) defines a new subtype of frontotemporal lobar degeneration (FTLD). FTLD is characterized by progressive alteration in cognitions and it preferentially affects the superficial layers of frontotemporal cortex. Mutation of FUS is linked to...

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Détails bibliographiques
Auteurs principaux: Huang, Cao, Tong, Jianbin, Bi, Fangfang, Wu, Qinxue, Huang, Bo, Zhou, Hongxia, Xia, Xu-Gang
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3471393/
https://ncbi.nlm.nih.gov/pubmed/22833456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/dds299
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