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Entorhinal cortical neurons are the primary targets of FUS mislocalization and ubiquitin aggregation in FUS transgenic rats

Ubiquitin-positive inclusion containing Fused in Sarcoma (FUS) defines a new subtype of frontotemporal lobar degeneration (FTLD). FTLD is characterized by progressive alteration in cognitions and it preferentially affects the superficial layers of frontotemporal cortex. Mutation of FUS is linked to...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Huang, Cao, Tong, Jianbin, Bi, Fangfang, Wu, Qinxue, Huang, Bo, Zhou, Hongxia, Xia, Xu-Gang
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3471393/
https://ncbi.nlm.nih.gov/pubmed/22833456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/dds299
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