Chargement en cours...
Expression of ALS-linked TDP-43 mutant in astrocytes causes non-cell-autonomous motor neuron death in rats
Mutation of Tar DNA-binding protein 43 (TDP-43) is linked to amyotrophic lateral sclerosis. Although astrocytes have important roles in neuron function and survival, their potential contribution to TDP-43 pathogenesis is unclear. Here, we created novel lines of transgenic rats that express a mutant...
Enregistré dans:
| Auteurs principaux: | , , , , , , , , |
|---|---|
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
European Molecular Biology Organization
2013
|
| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3981181/ https://ncbi.nlm.nih.gov/pubmed/23714777 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2013.122 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|