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Profiling the Genes Affected by Pathogenic TDP-43 in Astrocytes

Mutation in TAR DNA binding protein 43 (TDP-43) is a causative factor of amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD). Neurodegeneration may not require the presence of pathogenic TDP-43 in all types of relevant cells. Rather, expression of pathogenic TDP-43 in ne...

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Detalhes bibliográficos
Main Authors: Huang, Cao, Huang, Bo, Bi, Fangfang, Yan, Linda H, Tong, Jianbin, Huang, Jufang, Xia, Xu-Gang, Zhou, Hongxia
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4066372/
https://ncbi.nlm.nih.gov/pubmed/24447103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.12660
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