Toll or Interleukin-1 Receptor (TIR) Domain-containing Adaptor Inducing Interferon-β (TRIF)-mediated Caspase-11 Protease Production Integrates Toll-like Receptor 4 (TLR4) Protein- and Nlrp3 Inflammasome-mediated Host Defense against Enteropathogens

Enteric pathogens represent a major cause of morbidity and mortality worldwide. Toll-like receptor (TLR) and inflammasome signaling are critical for host responses against these pathogens, but how these pathways are integrated remains unclear. Here, we show that TLR4 and the TLR adaptor TRIF are req...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Gurung, Prajwal, Malireddi, R. K. Subbarao, Anand, Paras K., Demon, Dieter, Walle, Lieselotte Vande, Liu, Zhiping, Vogel, Peter, Lamkanfi, Mohamed, Kanneganti, Thirumala-Devi
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2012
Soggetti:
Immunology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3464552/
https://ncbi.nlm.nih.gov/pubmed/22898816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.401406
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi