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SHANK-associated RH domain interacting protein (SHARPIN) is required for optimal NLRP3 inflammasome activation
The NLRP3 inflammasome is a multimeric protein complex assembled in response to a wide array of pathogens and danger-associated molecular patterns. Despite the ability of NLRP3 to respond to diverse cues, the mechanisms controlling assembly of this complex are contested. Recently published studies s...
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| Veröffentlicht in: | J Immunol |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4340749/ https://ncbi.nlm.nih.gov/pubmed/25637014 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1402951 |
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