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An NLRP3 inflammasome–triggered Th2-biased adaptive immune response promotes leishmaniasis

Leishmaniasis is a major tropical disease that can present with cutaneous, mucocutaneous, or visceral manifestation and affects millions of individuals, causing substantial morbidity and mortality in third-world countries. The development of a Th1-adaptive immune response is associated with resistan...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Gurung, Prajwal, Karki, Rajendra, Vogel, Peter, Watanabe, Makiko, Bix, Mark, Lamkanfi, Mohamed, Kanneganti, Thirumala-Devi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4362229/
https://ncbi.nlm.nih.gov/pubmed/25689249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI79526
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