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Concerted activation of the AIM2 and NLRP3 inflammasomes orchestrates host protection against Aspergillus infection
Invasive pulmonary aspergillosis is a leading cause of infection-associated mortality in immunocompromised individuals. Aspergillus fumigatus infection produces ligands that could activate inflammasomes but the contribution of these host defenses remains unclear. We show that two inflammasome recept...
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Publicado no: | Cell Host Microbe |
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Main Authors: | , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4359672/ https://ncbi.nlm.nih.gov/pubmed/25704009 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2015.01.006 |
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