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SHANK-associated RH domain interacting protein (SHARPIN) is required for optimal NLRP3 inflammasome activation

The NLRP3 inflammasome is a multimeric protein complex assembled in response to a wide array of pathogens and danger-associated molecular patterns. Despite the ability of NLRP3 to respond to diverse cues, the mechanisms controlling assembly of this complex are contested. Recently published studies s...

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書目詳細資料
發表在:J Immunol
Main Authors: Gurung, Prajwal, Lamkanfi, Mohamed, Kanneganti, Thirumala-Devi
格式: Artigo
語言:Inglês
出版: 2015
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4340749/
https://ncbi.nlm.nih.gov/pubmed/25637014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1402951
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