An Adaptive Src-PDGFRA-Raf Axis in Rhabdomyosarcoma

Alveolar rhabdomyosarcoma (aRMS) is a very aggressive sarcoma of children and young adults. Our previous studies have shown that small molecule inhibition of Pdgfra is initially very effective in an aRMS mouse model. However, slowly evolving, acquired resistance to a narrow-spectrum kinase inhibitor...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Abraham, Jinu, Chua, Ying Xuan, Glover, Jason M., Tyner, Jeffrey W., Loriaux, Marc M., Kilcoyne, Aoife, Giles, Francis J., Nelon, Laura D., Carew, Jennifer S., Ouyang, Yongjian, Michalek, Joel E., Pal, Ranadip, Druker, Brian J., Rubin, Brian P., Keller, Charles
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3463776/
https://ncbi.nlm.nih.gov/pubmed/22960170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2012.08.092
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker