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PDGFRβ reverses EphB4 signaling in alveolar rhabdomyosarcoma

Alveolar rhabdomyosarcoma (aRMS) is an aggressive myogenic childhood malignancy, not infrequently presenting as incurable metastatic disease. To identify therapeutic targets, we performed an unbiased tyrosine kinome RNA interference screen in primary cell cultures from a genetically engineered, cond...

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Detalhes bibliográficos
Main Authors: Aslam, M. Imran, Abraham, Jinu, Mansoor, Atiya, Druker, Brian J., Tyner, Jeffrey W., Keller, Charles
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4035936/
https://ncbi.nlm.nih.gov/pubmed/24733895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1403608111
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