PDGFRβ reverses EphB4 signaling in alveolar rhabdomyosarcoma

Alveolar rhabdomyosarcoma (aRMS) is an aggressive myogenic childhood malignancy, not infrequently presenting as incurable metastatic disease. To identify therapeutic targets, we performed an unbiased tyrosine kinome RNA interference screen in primary cell cultures from a genetically engineered, cond...

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Main Authors: Aslam, M. Imran, Abraham, Jinu, Mansoor, Atiya, Druker, Brian J., Tyner, Jeffrey W., Keller, Charles
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2014
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4035936/
https://ncbi.nlm.nih.gov/pubmed/24733895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1403608111
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