PDGFRβ reverses EphB4 signaling in alveolar rhabdomyosarcoma

Alveolar rhabdomyosarcoma (aRMS) is an aggressive myogenic childhood malignancy, not infrequently presenting as incurable metastatic disease. To identify therapeutic targets, we performed an unbiased tyrosine kinome RNA interference screen in primary cell cultures from a genetically engineered, cond...

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Bibliographic Details
Main Authors: Aslam, M. Imran, Abraham, Jinu, Mansoor, Atiya, Druker, Brian J., Tyner, Jeffrey W., Keller, Charles
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2014
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4035936/
https://ncbi.nlm.nih.gov/pubmed/24733895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1403608111
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