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An Adaptive Src-PDGFRA-Raf Axis in Rhabdomyosarcoma
Alveolar rhabdomyosarcoma (aRMS) is a very aggressive sarcoma of children and young adults. Our previous studies have shown that small molecule inhibition of Pdgfra is initially very effective in an aRMS mouse model. However, slowly evolving, acquired resistance to a narrow-spectrum kinase inhibitor...
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| Main Authors: | , , , , , , , , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2012
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3463776/ https://ncbi.nlm.nih.gov/pubmed/22960170 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2012.08.092 |
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