Evasion Mechanisms to Igf1r Inhibition in Rhabdomyosarcoma

Inhibition of the insulin-like growth factor 1 receptor (Igf1r) is an approach being taken in clinical trials to overcome the dismal outcome for metastatic alveolar rhabdomyosarcoma (ARMS), an aggressive muscle cancer of children and young adults. In our study, we address the potential mechanism(s)...

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Détails bibliographiques
Auteurs principaux: Abraham, Jinu, Prajapati, Suresh I., Nishijo, Koichi, Schaffer, Beverly S., Taniguchi, Eri, Kilcoyne, Aoife, McCleish, Amanda T., Nelon, Laura D., Giles, Francis G., Efstratiadis, Argiris, LeGallo, Robin D., Nowak, Brent M., Rubin, Brian P., Malempati, Suman, Keller, Charles
Format: Artigo
Langue:Inglês
Publié: 2011
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4109806/
https://ncbi.nlm.nih.gov/pubmed/21447712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-10-0695
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