Evasion Mechanisms to Igf1r Inhibition in Rhabdomyosarcoma

Inhibition of the insulin-like growth factor 1 receptor (Igf1r) is an approach being taken in clinical trials to overcome the dismal outcome for metastatic alveolar rhabdomyosarcoma (ARMS), an aggressive muscle cancer of children and young adults. In our study, we address the potential mechanism(s)...

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書誌詳細
主要な著者: Abraham, Jinu, Prajapati, Suresh I., Nishijo, Koichi, Schaffer, Beverly S., Taniguchi, Eri, Kilcoyne, Aoife, McCleish, Amanda T., Nelon, Laura D., Giles, Francis G., Efstratiadis, Argiris, LeGallo, Robin D., Nowak, Brent M., Rubin, Brian P., Malempati, Suman, Keller, Charles
フォーマット: Artigo
言語:Inglês
出版事項: 2011
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4109806/
https://ncbi.nlm.nih.gov/pubmed/21447712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-10-0695
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