(18)F-FDG MicroPET Imaging Detects Early Transient Response to an IGF1R Inhibitor in Genetically-Engineered Rhabdomyosarcoma Models

BACKGROUND: Alveolar rhabdomyosarcoma (ARMS) and embryonal rhabdomyosarcoma (ERMS) are among the most common and most treatment resistant soft tissue sarcomas of childhood. Here, we evaluated the potential of (18)F-Fluorodeoxyglucose (FDG) as a marker of therapeutic response to picropodophyllin (PPP...

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Detalhes bibliográficos
Main Authors: Soundararajan, Anuradha, Abraham, Jinu, Nelon, Laura D., Prajapati, Suresh I., Zarzabal, Lee Ann, Michalek, Joel E., McHardy, Stanton F., Hawkins, Douglas S., Malempati, Suman, Keller, Charles
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3924883/
https://ncbi.nlm.nih.gov/pubmed/22238194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pbc.24075
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