Preclinical Testing of Erlotinib in a Transgenic Alveolar Rhabdomyosarcoma Mouse Model

Rhabdomyosarcoma is an aggressive childhood malignancy, accounting for more than 50% of all soft-tissue sarcomas in children. Even with extensive therapy, the survival rate among alveolar rhabdomyosarcoma patients with advanced disease is only 20%. The receptor tyrosine kinase Epidermal Growth Facto...

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Main Authors: Abraham, Jinu, Nelon, Laura D., Kubicek, Courtney B., Kilcoyne, Aoife, Hampton, Sheila T., Zarzabal, Lee Ann, Giles, Francis J., Michalek, Joel E., Rubin, Brian P., Keller, Charles
Formato: Artigo
Idioma:Inglês
Publicado: Hindawi Publishing Corporation 2011
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3087964/
https://ncbi.nlm.nih.gov/pubmed/21559212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2011/130484
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