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Preclinical Testing of Tandutinib in a Transgenic Medulloblastoma Mouse Model

Overexpression of platelet-derived growth factor recep tor alpha (PDGFR-A) has been documented in association with primary tumors and metastasis in medulloblastoma. Tumors from our genetically engineered SHH-driven medulloblastoma mouse model overexpress PDGFR-A in primary tumors and thus this mouse...

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Detalhes bibliográficos
Publicado no:J Pediatr Hematol Oncol
Main Authors: Ohshima-Hosoyama, Sachiko, Davare, Monika A., Prajapati, Suresh I., Abraham, Jinu, Lal, Sangeet, Nelon, Laura D., Kilcoyne, Aoife, Giles, Francis J., Hanes, Martha A., Rubin, Brian P., Keller, Charles
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6250428/
https://ncbi.nlm.nih.gov/pubmed/22146535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MPH.0b013e3182309fe4
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