p53 Mediates TNF-Induced Epithelial Cell Apoptosis in IBD

Chronic ulcerative colitis (CUC) is characterized by increased intestinal epithelial cell (IEC) apoptosis associated with elevated tumor necrosis factor (TNF), inducible nitric oxide synthase (iNOS), and p53. We previously showed that p53 is increased in crypt IECs in human colitis and is needed for...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Goretsky, Tatiana, Dirisina, Ramanarao, Sinh, Preetika, Mittal, Navdha, Managlia, Elizabeth, Williams, David B., Posca, Daniela, Ryu, Hyunji, Katzman, Rebecca B., Barrett, Terrence A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Investigative Pathology 2012
Schlagworte:
Regular Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3463630/
https://ncbi.nlm.nih.gov/pubmed/22863952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2012.06.016
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge