p53 Mediates TNF-Induced Epithelial Cell Apoptosis in IBD

Chronic ulcerative colitis (CUC) is characterized by increased intestinal epithelial cell (IEC) apoptosis associated with elevated tumor necrosis factor (TNF), inducible nitric oxide synthase (iNOS), and p53. We previously showed that p53 is increased in crypt IECs in human colitis and is needed for...

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書誌詳細
主要な著者: Goretsky, Tatiana, Dirisina, Ramanarao, Sinh, Preetika, Mittal, Navdha, Managlia, Elizabeth, Williams, David B., Posca, Daniela, Ryu, Hyunji, Katzman, Rebecca B., Barrett, Terrence A.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Investigative Pathology 2012
主題:
Regular Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3463630/
https://ncbi.nlm.nih.gov/pubmed/22863952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2012.06.016
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