Epithelial TNF receptor signaling promotes mucosal repair in IBD

TNF plays an integral role in inflammatory bowel disease (IBD) as evidenced by the dramatic therapeutic responses in Crohn’s disease (CD) patients induced by chimeric anti-TNF mAbs. However, treatment of CD patients with etanercept, a decoy receptor that binds soluble TNF, fails to improve disease....

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Опубликовано в: :J Immunol
Главные авторы: Bradford, Emily M, Ryu, Stacy H, Singh, Ajay Pal, Lee, Goo, Goretsky, Tatiana, Sinh, Preetika, Williams, David B, Cloud, Amber L, Gounaris, Elias, Patel, Vihang, Lamping, Olivia F, Lynch, Evan B, Moyer, Mary Pat, De Plaen, Isabelle G, Shealy, David J, Yang, Guang-Yu, Barrett, Terrence A
Формат: Artigo
Язык:Inglês
Опубликовано: 2017
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5568528/
https://ncbi.nlm.nih.gov/pubmed/28747340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1601066
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