Epithelial TNF receptor signaling promotes mucosal repair in IBD

TNF plays an integral role in inflammatory bowel disease (IBD) as evidenced by the dramatic therapeutic responses in Crohn’s disease (CD) patients induced by chimeric anti-TNF mAbs. However, treatment of CD patients with etanercept, a decoy receptor that binds soluble TNF, fails to improve disease....

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Publicado en:J Immunol
Main Authors: Bradford, Emily M, Ryu, Stacy H, Singh, Ajay Pal, Lee, Goo, Goretsky, Tatiana, Sinh, Preetika, Williams, David B, Cloud, Amber L, Gounaris, Elias, Patel, Vihang, Lamping, Olivia F, Lynch, Evan B, Moyer, Mary Pat, De Plaen, Isabelle G, Shealy, David J, Yang, Guang-Yu, Barrett, Terrence A
Formato: Artigo
Idioma:Inglês
Publicado: 2017
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5568528/
https://ncbi.nlm.nih.gov/pubmed/28747340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1601066
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