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Epithelial TNF receptor signaling promotes mucosal repair in IBD

TNF plays an integral role in inflammatory bowel disease (IBD) as evidenced by the dramatic therapeutic responses in Crohn’s disease (CD) patients induced by chimeric anti-TNF mAbs. However, treatment of CD patients with etanercept, a decoy receptor that binds soluble TNF, fails to improve disease....

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:J Immunol
Päätekijät: Bradford, Emily M, Ryu, Stacy H, Singh, Ajay Pal, Lee, Goo, Goretsky, Tatiana, Sinh, Preetika, Williams, David B, Cloud, Amber L, Gounaris, Elias, Patel, Vihang, Lamping, Olivia F, Lynch, Evan B, Moyer, Mary Pat, De Plaen, Isabelle G, Shealy, David J, Yang, Guang-Yu, Barrett, Terrence A
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2017
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5568528/
https://ncbi.nlm.nih.gov/pubmed/28747340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1601066
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