2325: Steroid therapy limits stem cell activation required to enact mucosal healing in inflammatory bowel disease

OBJECTIVES/SPECIFIC AIMS: Intestinal stem cells (ISC) primarily act in the repair of ulcerated epithelium, and their proliferative capacity relies on Wnt/β-catenin signaling. However, the role of GCs on basal epithelial cell signaling has not been fully characterized. The objective of this study was...

Full description

Saved in:
Bibliographic Details
Published in:J Clin Transl Sci
Main Authors: Brady Lynch, Evan, Goretsky, Tatiana, Bradford, Emily, Gao, Tianyan, Barrett, Terrence
Format: Artigo
Language:Inglês
Published: Cambridge University Press 2018
Subjects:
Mechanistic Basic to Clinical
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6799258/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1017/cts.2017.221
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items