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2325: Steroid therapy limits stem cell activation required to enact mucosal healing in inflammatory bowel disease

OBJECTIVES/SPECIFIC AIMS: Intestinal stem cells (ISC) primarily act in the repair of ulcerated epithelium, and their proliferative capacity relies on Wnt/β-catenin signaling. However, the role of GCs on basal epithelial cell signaling has not been fully characterized. The objective of this study was...

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Vydáno v:J Clin Transl Sci
Hlavní autoři: Brady Lynch, Evan, Goretsky, Tatiana, Bradford, Emily, Gao, Tianyan, Barrett, Terrence
Médium: Artigo
Jazyk:Inglês
Vydáno: Cambridge University Press 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6799258/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1017/cts.2017.221
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