p53 Mediates TNF-Induced Epithelial Cell Apoptosis in IBD

Chronic ulcerative colitis (CUC) is characterized by increased intestinal epithelial cell (IEC) apoptosis associated with elevated tumor necrosis factor (TNF), inducible nitric oxide synthase (iNOS), and p53. We previously showed that p53 is increased in crypt IECs in human colitis and is needed for...

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Détails bibliographiques
Auteurs principaux: Goretsky, Tatiana, Dirisina, Ramanarao, Sinh, Preetika, Mittal, Navdha, Managlia, Elizabeth, Williams, David B., Posca, Daniela, Ryu, Hyunji, Katzman, Rebecca B., Barrett, Terrence A.
Format: Artigo
Langue:Inglês
Publié: American Society for Investigative Pathology 2012
Sujets:
Regular Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3463630/
https://ncbi.nlm.nih.gov/pubmed/22863952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2012.06.016
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