5-ASA inhibits epithelial β-catenin activation in chronic ulcerative colitis

BACKGROUND & AIMS: 5-aminosalicylic acid (5-ASA) is a mainstay therapeutic agent in chronic ulcerative colitis (CUC) where it reverses crypt architectural changes and reduces colitis-associated cancer (CAC). The present study addressed the possibility that 5-ASA reduces β-catenin-associated prog...

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Autori principali: Brown, Jeffrey B., Lee, Goo, Managlia, Elizabeth, Grimm, Gery R., Dirisina, Ramanarao, Goretsky, Tatiana, Cheresh, Paul, Blatner, Nichole R., Khazaie, Khashayarsha, Yang, Guang-Yu, Li, Linheng, Barrett, Terrence A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2819654/
https://ncbi.nlm.nih.gov/pubmed/19879273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2009.10.038
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