Phosphoinositide 3-Kinase Signaling Mediates □-Catenin Activation in Intestinal Epithelial Stem and Progenitor Cells in Colitis

BACKGROUND & AIMS: Mechanisms responsible for crypt architectural distortion in chronic ulcerative colitis (CUC) are not well understood. Data indicate that Akt signaling cooperates with Wnt to activate β-catenin in intestinal stem and progenitor cells through phosphorylation at Ser552 (P-β-cate...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Lee, Goo, Goretsky, Tatiana, Managlia, Elizabeth, Dirisina, Ramanarao, Singh, Ajay Pal, Brown, Jeffrey B, May, Randal, Yang, Guang-Yu, Ragheb, Josette William, Evers, B Mark, Weber, Christopher R., Turner, Jerrold R, He, Xi C, Katzman, Rebecca B., Li, Linheng, Barrett, Terrence A
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2930080/
https://ncbi.nlm.nih.gov/pubmed/20580720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2010.05.037
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker