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Identification and analysis of hepatitis C virus NS3 helicase inhibitors using nucleic acid binding assays
Typical assays used to discover and analyze small molecules that inhibit the hepatitis C virus (HCV) NS3 helicase yield few hits and are often confounded by compound interference. Oligonucleotide binding assays are examined here as an alternative. After comparing fluorescence polarization (FP), homo...
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| Główni autorzy: | , , , , , , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Oxford University Press
2012
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3458564/ https://ncbi.nlm.nih.gov/pubmed/22740655 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks623 |
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