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Benzothiazole and Pyrrolone Flavivirus Inhibitors Targeting the Viral Helicase

The flavivirus nonstructural protein 3 (NS3) is a protease and helicase, and on the basis of its similarity to its homologue encoded by the hepatitis C virus (HCV), the flavivirus NS3 might be a promising drug target. Few flavivirus helicase inhibitors have been reported, in part, because few specif...

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Detalhes bibliográficos
Publicado no:ACS Infect Dis
Main Authors: Sweeney, Noreena L., Hanson, Alicia M., Mukherjee, Sourav, Ndjomou, Jean, Geiss, Brian J., Steel, J. Jordan, Frankowski, Kevin J., Li, Kelin, Schoenen, Frank J., Frick, David N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4444071/
https://ncbi.nlm.nih.gov/pubmed/26029739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/id5000458
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