Cloning and heterologous expression of Plasmodium ovale dihydrofolate reductase-thymidylate synthase gene

Plasmodial bifunctional dihydrofolate reductase-thymidylate synthase (DHFR-TS) is a validated antimalarial drug target. In this study, expression of the putative dhfr-ts of Plasmodium ovale rescued the DHFR chemical knockout and a TS null bacterial strain, demonstrating its DHFR and TS catalytic fun...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Hoofdauteurs: Tirakarn, Srisuda, Riangrungroj, Pinpunya, Kongsaeree, Palangpon, Imwong, Mallika, Yuthavong, Yongyuth, Leartsakulpanich, Ubolsree
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Elsevier 2012
Onderwerpen:
Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3444756/
https://ncbi.nlm.nih.gov/pubmed/22234170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.parint.2011.12.004
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items